참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Water | HCID 962 | — |
| 반응물 | 1-(2-Hydroxy-1-naphthyl)ethan-1-one | HCID 68455 | — |
| 촉매 | Zinc | HCID 23994 | — |
| 촉매 | Mercuric Chloride | HCID 24085 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 2-Naphthol, 1-ethyl- | HCID 3014975 | 84.3% |
반응 단계
A single neck round-bottom flask was charged with 2.3 g of zinc, 0.23 g of HgCl2 and 4 mL of water. Then 37% HCl (0.1 mL) was added and the mixture stirred for 5 minutes. After this, 3 mL of toluene and 3.4 mL of 37% HCl were added and finally 1 g (5.37 mmol) of 1-(2-hydroxynaphthalen-1-yl)ethanone was added portion wise. The resulting mixture was heated at 110° C. for 18 h. The phases were separated and the organic layer was dried over anhydrous sodium sulfate, filtered, and concentrated in vacuo to afford 780 mg (84% yield) of 1-ethylnaphthalen-2-ol as brown solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08906946B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_12 |
|---|
| ORD ID | ord-2c3e26fb70f34b4fba43c97b6d55b38f |
|---|
| 출처 메모 | uspto-grants-2014_12 |
|---|
