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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1401844생성일: 2026년 10월 26일

2-Bromo-1-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethan-1-one → 1-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]-1,4-diazepane

https://huagongshe.com/reaction/1401844

반응식

참여 물질

역할이름HCID투입량
반응물2-Bromo-1-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethan-1-oneHCID 2801337—
반응물4-Thiocarbamoyl-1,4-diazepane-1-carboxylic acid tert-butyl esterHCID 86671827—
생성물1-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]-1,4-diazepaneHCID 53311543—

반응 단계

The preparation is carried out as already described starting from 1.12 g (4.55 mmol) of 4-thiocarbamoyl-1,4-diazepane-1-carboxylic acid tert-butyl ester from step a and 1.93 g (6.25 mmol) of 2-bromo-1-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08907098B2
출처 데이터셋uspto-grants-2014_12
ORD IDord-afa24e65d6414065ab068d5c42c7e3ee
출처 메모uspto-grants-2014_12