Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3-{4-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]-1,4-diazepan-1-yl}propan-1-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 3-Chloro-1-propanol | HCID 12313 | — |
| 반응물 | 1-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]-1,4-diazepane | HCID 53311543 | — |
| 생성물 | 3-{4-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]-1,4-diazepan-1-yl}propan-1-ol | HCID 67324254 | — |
반응 단계
The preparation is carried out as already described starting from 95 mg (0.244 mmol) of 1-[4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]-1,4-diazepane and 30 μl (0.321 mmol) of 3-chloropropan-1-ol. The product is in the form of the hydrochloride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08907098B2 |
| 출처 데이터셋 | uspto-grants-2014_12 |
| ORD ID | ord-ff0b552a1687452ea236820f40a5016a |
| 출처 메모 | uspto-grants-2014_12 |