4-Chlorophenylacetyl chloride → Ethyl 3-[2-(4-chlorophenyl)-n-phenylacetamido]propanoate

반응식

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9](Cl)=[O:10])=[CH:4][CH:3]=1.[C:12]1([NH:18][CH2:19][CH2:20][C:21]([O:23][CH2:24][CH3:25])=[O:22])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([N:18]([CH2:19][CH2:20][C:21]([O:23][CH2:24][CH3:25])=[O:22])[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[O:10])=[CH:4][CH:3]=1

참가 물질

반응물 2

HCID 906924-Chlorophenylacetyl chloride

HCID 10910393beta-Alanine, N-phenyl-, ethyl ester

생성물 1

HCID 66759495Ethyl 3-[2-(4-chlorophenyl)-n-phenylacetamido]propanoate

실험 절차

By a procedure similar to that of example 1.115.1, starting from 4-chlorophenylacetyl chloride and ethyl N-phenyl-3-aminopropionate, ethyl 3-[2-(4-chlorophenyl)-N-phenylacetamido]propanoate was obtained as light tan oil.

출처 및 근거

ORD 기록: ord-c552935ed92a4cf8baba9a2a9e5d2291
출처 데이터셋: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08912186B2

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