3-tert-Butylbenzoyl chloride → 3-tert-butyl-N-(3-(2-oxo-1,2-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)benzamide
반응식
[NH2:1][C:2]1[CH:3]=[C:4]([CH:17]=[CH:18][CH:19]=1)[O:5][C:6]1[C:15]2[NH:14][C:13](=[O:16])[CH:12]=[N:11][C:10]=2[N:9]=[CH:8][CH:7]=1.[C:20]([C:24]1[CH:25]=[C:26]([CH:30]=[CH:31][CH:32]=1)[C:27](Cl)=[O:28])([CH3:23])([CH3:22])[CH3:21]>>[C:20]([C:24]1[CH:25]=[C:26]([CH:30]=[CH:31][CH:32]=1)[C:27]([NH:1][C:2]1[CH:19]=[CH:18][CH:17]=[C:4]([O:5][C:6]2[C:15]3[NH:14][C:13](=[O:16])[CH:12]=[N:11][C:10]=3[N:9]=[CH:8][CH:7]=2)[CH:3]=1)=[O:28])([CH3:23])([CH3:21])[CH3:22]참가 물질
3
실험 절차
Method G1 was used with 8-(3-aminophenoxy)pyrido[2,3-b]pyrazin-2(1H)-one and 3-tertbutylbenzoyl chloride to afford the title compound as a white solid (14 mg, 22%).
출처 및 근거
- ORD 기록
- ord-c8460319c11b4a85875fb0852c8e7f3d
- 출처 데이터셋
- uspto-grants-2014_12