Trifluoroacetic acid → 5-[2-Amino-5-({4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}ethynyl)pyrimidin-4-yl]-2-(5-chloro-2-methylphenyl)-1H-pyrrole-3-carboxamide

반응식

FC(F)(F)C(O)=O.[NH2:8][C:9]1[N:14]=[C:13]([C:15]2[N:19](COCC[Si](C)(C)C)[C:18]([C:28]3[CH:33]=[C:32]([Cl:34])[CH:31]=[CH:30][C:29]=3[CH3:35])=[C:17]([C:36]([NH2:38])=[O:37])[CH:16]=2)[C:12]([C:39]#[C:40][C:41]2[CH:46]=[CH:45][C:44]([C:47]([N:49]3[CH2:54][CH2:53][N:52]([CH3:55])[CH2:51][CH2:50]3)=[O:48])=[CH:43][CH:42]=2)=[CH:11][N:10]=1>C(Cl)Cl>[NH2:8][C:9]1[N:14]=[C:13]([C:15]2[NH:19][C:18]([C:28]3[CH:33]=[C:32]([Cl:34])[CH:31]=[CH:30][C:29]=3[CH3:35])=[C:17]([C:36]([NH2:38])=[O:37])[CH:16]=2)[C:12]([C:39]#[C:40][C:41]2[CH:42]=[CH:43][C:44]([C:47]([N:49]3[CH2:54][CH2:53][N:52]([CH3:55])[CH2:51][CH2:50]3)=[O:48])=[CH:45][CH:46]=2)=[CH:11][N:10]=1