Benzyl Bromide → 5-Benzylpyrrolidin-2-One

반응식

[NH:1]1[C:5](=O)[CH2:4][CH2:3][C:2]1=[O:7].[CH2:8](Br)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[CH2:8]([CH:5]1[NH:1][C:2](=[O:7])[CH2:3][CH2:4]1)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

참가 물질

반응물 2

HCID 7498Benzyl Bromide

HCID 11439Succinimide

생성물 1

HCID 998815-Benzylpyrrolidin-2-One

실험 절차

5-Benzylpyrrolidin-2-one is synthesized from pyrrolidine-2,5-dione and benzyl bromide according to S. Lebrun et al. (Tetrahedron Asymmetry 2003, 14, 2625-2632).

출처 및 근거

ORD 기록: ord-e72a03d9be524a91a232b6634b2012d8
출처 데이터셋: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08912329B2

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