3-Aminophenylboronic acid → 3-{1-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-1H-pyrrolo[3,2-b]pyridin-6-yl}aniline

HRID 1404586

반응식

HRID 1404586 반응식
Br[C:2]1[CH:3]=[C:4]2[N:10]([O:11][CH:12]([C:14]3[C:19]([Cl:20])=[CH:18][CH:17]=[C:16]([F:21])[C:15]=3[Cl:22])[CH3:13])[CH:9]=[CH:8][C:5]2=[N:6][CH:7]=1.[NH2:23][C:24]1[CH:25]=[C:26](B(O)O)[CH:27]=[CH:28][CH:29]=1>>[Cl:22][C:15]1[C:16]([F:21])=[CH:17][CH:18]=[C:19]([Cl:20])[C:14]=1[CH:12]([O:11][N:10]1[C:4]2[C:5](=[N:6][CH:7]=[C:2]([C:28]3[CH:29]=[C:24]([CH:25]=[CH:26][CH:27]=3)[NH2:23])[CH:3]=2)[CH:8]=[CH:9]1)[CH3:13]

참가 물질

3

반응물 2

HCID 922693-Aminophenylboronic acidHCID 674584186-bromo-1-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-1H-pyrrolo[3,2-b]pyridine

생성물 1

HCID 585323503-{1-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-1H-pyrrolo[3,2-b]pyridin-6-yl}aniline

실험 절차

The entitled compound was prepared from 6-bromo-1-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-1H-pyrrolo[3,2-b]pyridine and (3-aminophenyl)boronic acid according to the procedure described in example 4.

출처 및 근거

ORD 기록
ord-d483363102444250a651b79c1afc4325
출처 데이터셋
uspto-grants-2014_12
특허 번호
US08912330B2

연결된 노트

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