Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,3,5-Trifluorobenzyl alcohol → 4-{4-Fluoro-2-[(2,3,5-trifluorobenzyl)oxy]phenyl}-N-{3-[(methylsulfonyl)methyl]-phenyl}-1,3,5-triazin-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,3,5-Trifluorobenzyl alcohol | HCID 2777030 | — |
| 반응물 | 4-(2,4-difluorophenyl)-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine | HCID 70976524 | — |
| 생성물 | 4-{4-Fluoro-2-[(2,3,5-trifluorobenzyl)oxy]phenyl}-N-{3-[(methylsulfonyl)methyl]-phenyl}-1,3,5-triazin-2-amine | HCID 66576056 | — |
반응 단계
Starting with 4-(2,4-difluorophenyl)-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine (70 mg; 0.184 mmol), intermediate 42.1, and 2,3,5-trifluorobenzyl alcohol (119 mg; 0.736 mmol), example 84 was prepared analogously to the procedure for the preparation of example 42.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08916557B2 |
| 출처 데이터셋 | uspto-grants-2014_12 |
| ORD ID | ord-c140f3d4ab1b492d98feddd62f9b30b4 |
| 출처 메모 | uspto-grants-2014_12 |