Allyl bromide → HCID 86723056, 화합물

반응식

[C:1]1(=[O:15])[C:10]2[C:5]3=[C:6]([CH2:11][CH2:12][CH2:13][N:4]3[C:3](=[O:14])[NH:2]1)[CH:7]=[CH:8][CH:9]=2.[CH2:16](Br)[CH:17]=[CH2:18]>>[CH2:18]([N:2]1[C:1](=[O:15])[C:10]2[C:5]3=[C:6]([CH2:11][CH2:12][CH2:13][N:4]3[C:3]1=[O:14])[CH:7]=[CH:8][CH:9]=2)[CH:17]=[CH2:16]

참가 물질

반응물 2

HCID 7841Allyl bromide

HCID 11608121HCID 11608121, 화합물

생성물 1

HCID 86723056HCID 86723056, 화합물수율 89%

실험 절차

Starting from 6,7-dihydropyrido[3,2,1-ij]quinazoline-1,3 (2H,5H)-dione (prepared according to WO 2010/079206) and allyl bromide and using Procedure E, the title intermediate was obtained as a colourless solid (0.393 g; 89% yield).

출처 및 근거

ORD 기록: ord-27d5011f808e45ff8d4d57ead5e0fb6f
출처 데이터셋: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08916573B2

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