Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-5-methylbenzoic acid → 2-amino-5-methyl-N-{3-[(R)-2-oxo-3-(3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-6-yl)-oxazolidin-5-yl]-propyl}-benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-5-methylbenzoic acid | HCID 76255 | — |
| 반응물 | 6-[(R)-5-(3-amino-propyl)-2-oxo-oxazolidin-3-yl]-4H-benzo[1,4]thiazin-3-one | HCID 67303587 | — |
| 생성물 | 2-amino-5-methyl-N-{3-[(R)-2-oxo-3-(3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-6-yl)-oxazolidin-5-yl]-propyl}-benzamide | HCID 86723058 | 56% |
반응 단계
Starting from 2-amino-5-methylbenzoic acid and 6-[(R)-5-(3-amino-propyl)-2-oxo-oxazolidin-3-yl]-4H-benzo[1,4]thiazin-3-one (described in WO 2010/041219) and using Procedure D, the title compound was obtained as a beige solid (130 mg; 56% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08916573B2 |
| 출처 데이터셋 | uspto-grants-2014_12 |
| ORD ID | ord-48e0e54ea24543bcb26c74ff7be31e8f |
| 출처 메모 | uspto-grants-2014_12 |