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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1405622생성일: 2026년 10월 27일

2-Amino-6-chlorobenzoic acid → 2-amino-6-chloro-N-{3-[(R)-2-oxo-3-(3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-6-yl)-oxazolidin-5-yl]-propyl}-benzamide

https://huagongshe.com/reaction/1405622

반응식

참여 물질

역할이름HCID투입량
반응물2-Amino-6-chlorobenzoic acidHCID 75071—
반응물6-[(R)-5-(3-amino-propyl)-2-oxo-oxazolidin-3-yl]-4H-benzo[1,4]thiazin-3-oneHCID 67303587—
생성물2-amino-6-chloro-N-{3-[(R)-2-oxo-3-(3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-6-yl)-oxazolidin-5-yl]-propyl}-benzamideHCID 8672306046%

반응 단계

Starting from 2-amino-6-chlorobenzoic acid and 6-[(R)-5-(3-amino-propyl)-2-oxo-oxazolidin-3-yl]-4H-benzo[1,4]thiazin-3-one (described in WO 2010/041219) and using Procedure D, the title compound was obtained as a beige solid (100 mg; 46% yield).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08916573B2
출처 데이터셋uspto-grants-2014_12
ORD IDord-dff2632bcf434510834c72e0ece411a4
출처 메모uspto-grants-2014_12