4-(2-Isopropyl-phenoxy)-benzylamine → Pyrimidine-5-carboxylic acid-{1-[4-(2-isopropyl-phenoxy)-benzylcarbamoyl]-cyclopropyl}-amide
반응식
[N:1]1[CH:6]=[C:5]([C:7]([NH:9][C:10]2([C:13]([OH:15])=O)[CH2:12][CH2:11]2)=[O:8])[CH:4]=[N:3][CH:2]=1.[CH:16]([C:19]1[CH:33]=[CH:32][CH:31]=[CH:30][C:20]=1[O:21][C:22]1[CH:29]=[CH:28][C:25]([CH2:26][NH2:27])=[CH:24][CH:23]=1)([CH3:18])[CH3:17]>>[CH:16]([C:19]1[CH:33]=[CH:32][CH:31]=[CH:30][C:20]=1[O:21][C:22]1[CH:29]=[CH:28][C:25]([CH2:26][NH:27][C:13]([C:10]2([NH:9][C:7]([C:5]3[CH:4]=[N:3][CH:2]=[N:1][CH:6]=3)=[O:8])[CH2:11][CH2:12]2)=[O:15])=[CH:24][CH:23]=1)([CH3:18])[CH3:17]참가 물질
3
실험 절차
Analogously to Example (7c) the title compound was prepared from 1-[(pyrimidine-5-carbonyl)-amino]-cyclopropanecarboxylic acid and 4-(2-isopropyl-phenoxy)-benzylamine.
출처 및 근거
- ORD 기록
- ord-a638a1e5cf074e429153822dc511e10f
- 출처 데이터셋
- uspto-grants-2014_12