Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hexane → methyl O-benzyl-N-(tert-butoxycarbonyl)homoserinate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hexane | HCID 8058 | — |
| 반응물 | Trimethylsilyldiazomethane | HCID 167693 | — |
| 반응물 | O-Benzyl-N-(tert-butoxycarbonyl)-L-homoserine | HCID 15058464 | — |
| 용매 | Benzene methanol | HCID 21927730 | — |
| 생성물 | methyl O-benzyl-N-(tert-butoxycarbonyl)homoserinate | HCID 54564501 | — |
반응 단계
To O-benzyl-N-(tert-butoxycarbonyl)homoserine (5.8 g, 18.9 mmol) in 20% methanol/benzene (72 mL) is added 2M trimethylsilyldiazomethane in hexane (12.3 mL, 24.5 mmol), and the reaction stirred at room temperature 1.5 h. The solution is concentrated under reduced pressure to give the title compound in pure form. ESI MS m/z 324.2 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07727997B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-92306b3288f94584930245ab3ab8e0d5 |
| 출처 메모 | uspto-grants-2010_06 |