6-Bromonicotinic acid → HCID 66759906, 화합물

HRID 1409717노트

반응식

HRID 1409717 반응식
Br[C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][N:3]=1.CC1(C)C(C)(C)OB([C:19]2[O:23][C:22]([Si](C(C)C)(C(C)C)C(C)C)=[N:21][CH:20]=2)O1>>[O:23]1[C:19]([C:2]2[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][N:3]=2)=[CH:20][N:21]=[CH:22]1

참가 물질

3

반응물 2

HCID 2389326-Bromonicotinic acidHCID 442243115-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(tris(propan-2-yl)silyl)-1,3-oxazole

생성물 1

HCID 66759906HCID 66759906, 화합물

실험 절차

The title compound is prepared from 6-bromo-nicotinic acid and 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-[tris(isopropyl)silyl]-oxazole and following a procedure analogous to that described in Intermediate 45. Mass spectrum (ESI+): m/z=189 [M−H]−.

출처 및 근거

ORD 기록
ord-791d3be931144e0b8cdb049ab7d56d86
출처 데이터셋
uspto-grants-2014_12
특허 번호
US08921398B2

반응 노트

불러오는 중…