HCID 86686164, 화합물 → HCID 86686163, 화합물

HRID 1409756노트

반응식

HRID 1409756 반응식
[C:1]([N:3]1[CH2:8][CH2:7][CH:6]([N:9]([CH:27]2[CH2:29][CH2:28]2)[C:10]([C:12]2[CH:13]=[N:14][C:15]([C:18]3[CH:23]=[CH:22][C:21]([CH2:24][C:25]#[N:26])=[CH:20][CH:19]=3)=[N:16][CH:17]=2)=[O:11])[CH2:5][CH2:4]1)#[N:2].[OH:30][NH:31][C:32](=N)[CH2:33][CH3:34]>>[CH:27]1([N:9]([CH:6]2[CH2:5][CH2:4][N:3]([C:1]3[O:30][N:31]=[C:32]([CH2:33][CH3:34])[N:2]=3)[CH2:8][CH2:7]2)[C:10]([C:12]2[CH:17]=[N:16][C:15]([C:18]3[CH:19]=[CH:20][C:21]([CH2:24][C:25]#[N:26])=[CH:22][CH:23]=3)=[N:14][CH:13]=2)=[O:11])[CH2:28][CH2:29]1

참가 물질

3

반응물 2

HCID 86686164HCID 86686164, 화합물HCID 178458070HCID 178458070, 화합물

생성물 1

HCID 86686163HCID 86686163, 화합물

실험 절차

The title compound is prepared from 2-(4-cyanomethyl-phenyl)-pyrimidine-5-carboxylic acid (1-cyano-piperidin-4-yl)-cyclopropyl-amide and N-hydroxy-propionamidine following a procedure analogous to that described in Example 6. LC (method 3): tR=1.86 min; Mass spectrum (ESI+): m/z=458 [M+H]+.

출처 및 근거

ORD 기록
ord-0fb86acdfc004561a166636b0563c95d
출처 데이터셋
uspto-grants-2014_12
특허 번호
US08921398B2

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