HCID 67230022, 화합물 → HCID 59529808, 화합물
반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([NH:10][C:11](=[O:13])[CH3:12])[CH3:9])=[CH:4][C:3]=1[N:14]=[C:15]=[S:16].[NH2:17][C:18]1[CH:19]=[C:20]([CH:31]=[CH:32][C:33]=1[NH:34][CH3:35])[C:21]([NH:23][C:24]1[CH:29]=[CH:28][C:27]([Br:30])=[CH:26][CH:25]=1)=[O:22]>CN(C=O)C>[C:11]([NH:10][CH:8]([C:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[C:3]([NH:14][C:15](=[S:16])[NH:17][C:18]2[CH:19]=[C:20]([CH:31]=[CH:32][C:33]=2[NH:34][CH3:35])[C:21]([NH:23][C:24]2[CH:25]=[CH:26][C:27]([Br:30])=[CH:28][CH:29]=2)=[O:22])[CH:4]=1)[CH3:9])(=[O:13])[CH3:12]참가 물질
4
실험 절차
N-[1-(4-Chloro-3-isothiocyanatophenyl)ethyl]acetamide in DMF (2 mL) was added to a mixture of 3-amino-N-(4-bromophenyl)-4-methylaminobenzamide (87 mg, 0.2 mmol, crude material from the step above) in DMF (2 mL) at rt. The mixture was stirred at rt overnight and concentrated. The residue was purified by chromatography to give the sub-title compound. Yield: 130 mg.