Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trimethylsilyldiazomethane → Methyl 3-bromo-5-(hydroxymethyl)benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trimethylsilyldiazomethane | HCID 167693 | — |
| 반응물 | 3-Bromo-5-(hydroxymethyl)benzoic acid | HCID 8167127 | — |
| 용매 | Benzene methanol | HCID 21927730 | — |
| 생성물 | Methyl 3-bromo-5-(hydroxymethyl)benzoate | HCID 11356988 | — |
반응 단계
To 3-bromo-5-(hydroxymethyl)benzoic acid (7.0 g, 30 mmol) in 20% methanol/benzene (100 mL) is added trimethylsilyldiazomethane (2M in hexanes), and the reaction is stirred 16 h. The reaction is concentrated under reduced pressure to afford the title compound. ESI MS m/z 244.0 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07727997B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-a362f1bc326742dc8cca9713458fb263 |
| 출처 메모 | uspto-grants-2010_06 |