(2E)-3-(2,3-Dihydro-5-benzofuranyl)-2-propenoic acid → HCID 57343917, 화합물
반응식
Cl.Cl.[NH:3]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([CH:12]2[CH2:17][CH2:16][CH:15]([NH:18][CH:19]([CH:23]3[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]3)[C:20]([NH2:22])=[O:21])[CH2:14][CH2:13]2)=[CH:4]1.[O:29]1[C:33]2[CH:34]=[CH:35][C:36](/[CH:38]=[CH:39]/[C:40](O)=[O:41])=[CH:37][C:32]=2[CH2:31][CH2:30]1>>[NH:3]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([CH:12]2[CH2:17][CH2:16][CH:15]([NH:18][CH:19]([CH:23]3[CH2:24][CH2:25][N:26]([C:40](=[O:41])/[CH:39]=[CH:38]/[C:36]4[CH:35]=[CH:34][C:33]5[O:29][CH2:30][CH2:31][C:32]=5[CH:37]=4)[CH2:27][CH2:28]3)[C:20]([NH2:22])=[O:21])[CH2:14][CH2:13]2)=[CH:4]1참가 물질
3
실험 절차
The title compound was prepared from the product of Example 1, step J, and trans-3-(2,3-dihydrobenzofuran-5-yl)prop-2-enoic acid, by the method of Example 1, step K, giving a solid that was mostly the more polar cyclohexyl diastereomer by LCMS. Mass spectrum (LCMS, ESI pos.) calcd. for C32H38N4O3: 527 (M+H). Found: 527
후처리
- customgiving a solid