Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
trans-3,5-Difluorocinnamic acid → HCID 178501619, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | trans-3,5-Difluorocinnamic acid | HCID 5374941 | — |
| 반응물 | Methyl 2-((4-(1H-indol-3-yl)cyclohexyl)amino)-2-(piperidin-4-yl)acetate | HCID 67774409 | — |
| 생성물 | HCID 178501619 | HCID 178501619 | — |
반응 단계
The title compound was prepared from methyl 2-(4-(1H-indol-3-yl)cyclohexyl)amino)-2-(piperidin-4-yl)acetate (from Example 24, step A) and trans-3,5-difluorocinnamic acid, by the method of Example 1, step K, giving a solid that was mostly the more polar cyclohexyl diastereomer by LCMS. Mass spectrum (LCMS, APCI pos.) calcd. for C31H35F2N3O3: 536 (M+H). Found: 536.3.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08921559B2 |
| 출처 데이터셋 | uspto-grants-2014_12 |
| ORD ID | ord-2ef06bb5c15e40cf9cccf8e4c244993d |
| 출처 메모 | uspto-grants-2014_12 |