Tetrahydrofuran → N-{4-[6-(4-trifluoromethyl-phenyl)-pyrimidin-4-yloxy]-benzothiazol-2-yl}-propionamide

반응식

[C:28]([CH2:29][CH3:30])(=[O:31])[Cl:32].[C:33]([N:34]=[P:35]1([N:36]([CH2:37][CH3:38])[CH2:39][CH3:40])[N:41]([CH3:42])[CH2:43][CH2:44][CH2:45][N:46]1[CH3:47])([CH3:48])([CH3:49])[CH3:50].[CH2:51]1[O:52][CH2:53][CH2:54][CH2:55]1.[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][c:11]([O:15][c:16]3[cH:17][cH:18][cH:19][c:20]4[c:21]3[n:22][c:23]([NH2:25])[s:24]4)[n:12][cH:13][n:14]2)[cH:7][cH:8]1)([F:26])[F:27]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][c:11]([O:15][c:16]3[cH:17][cH:18][cH:19][c:20]4[c:21]3[n:22][c:23]([NH:25][C:28]([CH2:29][CH3:30])=[O:31])[s:24]4)[n:12][cH:13][n:14]2)[cH:7][cH:8]1)([F:26])[F:27]