Water → 2-[(2-pyridylmethyl)thio]-1H-naphth[2,3-d]imidazole

HRID 1413107노트

반응식

HRID 1413107 반응식
[CH3:1][S:2][C:3]1[NH:7][C:6]2[CH:8]=[C:9]3[C:14](=[CH:15][C:5]=2[N:4]=1)[CH:13]=[CH:12][CH:11]=[CH:10]3.SC[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][N:19]=1.O>C(O)C>[N:19]1[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=1[CH2:1][S:2][C:3]1[NH:4][C:5]2[CH:15]=[C:14]3[C:9](=[CH:8][C:6]=2[N:7]=1)[CH:10]=[CH:11][CH:12]=[CH:13]3

참가 물질

5

반응물 3

HCID 962WaterHCID 2560712-PyridinemethanethiolHCID 128720792-(methylthio)-1H-naphtho[2,3-d]imidazole

생성물 1

HCID 223941842-[(2-pyridylmethyl)thio]-1H-naphth[2,3-d]imidazole수율 81.7%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

0.45 g of 2-methylthio-1H-naphth[2,3-d]imidazole and 0.65 g of 2-mercaptomethylpyridine were heated for 40 hours under reflux in 10 ml of ethanol. 10 ml of water were added to the homogeneous solution and the precipitate formed was filtered off. 0.50 g of 2-[(2-pyridylmethyl)thio]-1H-naphth[2,3-d]imidazole having a m.p. of 170° was obtained.

후처리

  1. customthe precipitate formed
  2. filtrationwas filtered off

출처 및 근거

ORD 기록
ord-912ef9e4fffc48e484a28a9f07d219fa
출처 데이터셋
uspto-grants-1981_02
특허 번호
US04248880

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