3-Aminobenzenesulfonic acid → 4-Phenyl-2-(3-sulfophenylamino)-thiazole

HRID 1413332노트

반응식

HRID 1413332 반응식
[CH2:1]([S:10][C:11]#[N:12])[C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)=O.[NH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([OH:23])(=[O:22])=[O:21])[CH:15]=1>[Cl-].[Zn+2].[Cl-].O>[C:4]1([C:2]2[N:12]=[C:11]([NH:13][C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([OH:23])(=[O:21])=[O:22])[CH:15]=3)[S:10][CH:1]=2)[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

참가 물질

5

반응물 2

HCID 84743-Aminobenzenesulfonic acidHCID 219693Phenacyl thiocyanate

생성물 1

HCID 202918054-Phenyl-2-(3-sulfophenylamino)-thiazole

시약·촉매·용매 2

HCID 3007855Zincchloride촉매HCID 962Water용매

실험 절차

132 parts of phenacyl thiocyanate, 38 parts of zinc chloride and 129 parts of 1-aminobenzene-3-sulfonic acid are together stirred with 750 parts of water for 20 hours at the boil. After the mixture has cooled, the product is filtered off and dried.

후처리

  1. temperatureAfter the mixture has cooled
  2. filtrationthe product is filtered off
  3. customdried

출처 및 근거

ORD 기록
ord-e475d43585464d9f8a762862e4edc5fc
출처 데이터셋
uspto-grants-1981_02
특허 번호
US04250090

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