Isobutylamine → 2-(3-chlorophenoxy)N-isobutylnicotinamide
반응식
[CH2:1]([NH2:5])[CH:2]([CH3:4])[CH3:3].[Cl:6][C:7]1[CH:8]=[C:9]([CH:20]=[CH:21][CH:22]=1)[O:10][C:11]1[N:19]=[CH:18][CH:17]=[CH:16][C:12]=1[C:13](Cl)=[O:14]>C1(C)C=CC=CC=1>[Cl:6][C:7]1[CH:8]=[C:9]([CH:20]=[CH:21][CH:22]=1)[O:10][C:11]1[N:19]=[CH:18][CH:17]=[CH:16][C:12]=1[C:13]([NH:5][CH2:1][CH:2]([CH3:4])[CH3:3])=[O:14]참가 물질
4
실험 절차
In the same manner as in Example 1(c) 1.4 grams (0.02 mole) isobutylamine and 2.7 grams (0.01 mole) of the acyl chloride produced in step (b) were combined in 50 milliliters toluene to yield 2.8 grams (92.1% of theoretical yield) of the desired product, m.p. 86°-87° C. The structure was confirmed by mass spectrometry.
후처리
- customto yield
출처 및 근거
- ORD 기록
- ord-5ca4ef4a074943e2a50da4c8c1a9315b
- 출처 데이터셋
- uspto-grants-1981_02
- 특허 번호
- US04251263
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