2-((4-Fluorophenyl)amino)-3-methylbutanoic acid → 3-Benzylpyrrolylmethyl 2-(4-fluorophenylamino)-3-methylbutanoate

반응식

[F:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][CH:9]([CH:13]([CH3:15])[CH3:14])[C:10]([OH:12])=[O:11])=[CH:4][CH:3]=1.[CH2:16]([C:23]1[CH:27]=[CH:26][NH:25][C:24]=1[CH2:28]O)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][CH:9]([CH:13]([CH3:15])[CH3:14])[C:10]([O:12][CH2:28][C:24]2[NH:25][CH:26]=[CH:27][C:23]=2[CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[O:11])=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 204827962-((4-Fluorophenyl)amino)-3-methylbutanoic acid

HCID 543430813-Benzyl-1-pyrrolylmethanol

생성물 1

HCID 202892923-Benzylpyrrolylmethyl 2-(4-fluorophenylamino)-3-methylbutanoate

실험 절차

The acid 2-(4-fluorophenylamino)-3-methylbutanoic acid is reacted with 3-benzylpyrrolylmethyl alcohol using the procedure of Example 3 to give 3-benzylpyrrolylmethyl 2-(4-fluorophenylamino)-3-methylbutanoate.

출처 및 근거

ORD 기록: ord-bdf0190b37e84e73a600bd1420e333a2
출처 데이터셋: uspto-grants-1981_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04252724

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