Chlorotrimethylsilane → HCID 54233991, 화합물

HRID 1413980노트

반응식

HRID 1413980 반응식
C[O:2][C:3]1([CH3:10])O[CH:8]2[CH:5]([CH2:6][CH2:7]2)[O:4]1.C[Si](C)(C)[Cl:13]>C(Cl)Cl>[Cl:13][C@@H:8]1[CH2:7][CH2:6][C@H:5]1[O:4][C:3](=[O:2])[CH3:10]

참가 물질

4

반응물 2

HCID 6397ChlorotrimethylsilaneHCID 12791329HCID 12791329, 화합물

생성물 1

HCID 54233991HCID 54233991, 화합물수율 89%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

14.4 g (0.1 mol) of 3-methoxy-3-methyl-2,4-dioxa-bicyclo[3,2,0]heptane (stereoisomer mixture) and 16.2 g (0.149 mol) of trimethylchlorosilane in 50 ml of methylene chloride are heated under reflux for 15 hours. Stripping off the solvent and fractional distillation of the residue gives 13.2 g (89%) of trans-1-chloro-2-acetoxy-cyclobutane. Boiling point10 66°, nD20 1.4472.

후처리

  1. temperatureunder reflux for 15 hours
  2. distillationStripping off the solvent and fractional distillation of the residue

출처 및 근거

ORD 기록
ord-a09ab096b7a2458994fbaa9555314fa2
출처 데이터셋
uspto-grants-1981_02
특허 번호
US04252738

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