Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrogen Bromide → 1-(Chloromethyl)adamantane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrogen Bromide | HCID 260 | — |
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Tricyclo(3.3.1.1'3,7)dec-1-ylmethanol | HCID 64556 | — |
| 반응물 | 1-(Bromomethyl)adamantane | HCID 1416304 | — |
| 촉매 | Zincchloride | HCID 3007855 | — |
| 촉매 | Zinc bromide | HCID 10421208 | — |
| 생성물 | 1-(Chloromethyl)adamantane | HCID 2103969 | 91% |
반응 단계
Chlorination reaction of 1-adamantyl methylalcohol which was obtained by the same method described in (1) was carried out under the same conditions for the bromination reaction shown in (2) except that zinc bromide and hydrobromic acid were replaced by zinc chloride and hydrochloric acid respectively. The product was purified by recrystallized from methanol. Melting point of 1-adamantyl methyl chloride thus obtained was 32°-34° C and the yield was 91%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04001223 |
| 출처 데이터셋 | uspto-grants-1977_01 |
| ORD ID | ord-fbbd2f48596345ff98bd1e3f739e32b8 |
| 출처 메모 | uspto-grants-1977_01 |