4,5-Diphenyl-4-oxazoline-2-thione → 2-Morpholinoethyl S-(4,5-diphenyloxazol-2-YL)-mercaptoacetate

반응식

Cl.Cl[CH2:3][C:4]([O:6][CH2:7][CH2:8][N:9]1[CH2:14][CH2:13][O:12][CH2:11][CH2:10]1)=[O:5].[C:15]1([C:21]2[NH:22][C:23](=[S:32])[O:24][C:25]=2[C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[C:15]1([C:21]2[N:22]=[C:23]([S:32][CH2:3][C:4]([O:6][CH2:7][CH2:8][N:9]3[CH2:14][CH2:13][O:12][CH2:11][CH2:10]3)=[O:5])[O:24][C:25]=2[C:26]2[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=2)[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

참가 물질

반응물 2

HCID 8536764,5-Diphenyl-4-oxazoline-2-thione

HCID 214866102-Morpholinoethyl chloroacetate hydrochloride

생성물 1

HCID 130125262-Morpholinoethyl S-(4,5-diphenyloxazol-2-YL)-mercaptoacetate

실험 절차

A 7.3 g aliquot of the thus prepared 2-morpholinoethyl chloroacetate hydrochloride was then reacted according to the procedure of Example 1 with 7.6 g 4,5-diphenyl-4-oxazolin-2-thione to give 2.4 g of the title compound.

출처 및 근거

ORD 기록: ord-6928eff3b1c449f4b22f7135facf53cc
출처 데이터셋: uspto-grants-1977_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04001228

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