2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline → 4-Amino-6,7-dimethoxy-2-[4-(5-n-butylthio-1,3,4-oxadiazole-2-carbonyl)-piperazin-1-yl]-quinazoline hydrochloride
반응식
[CH2:1]([S:5][C:6]1[O:10][C:9]([C:11]([Cl:13])=[O:12])=[N:8][N:7]=1)[CH2:2][CH2:3][CH3:4].[NH2:14][C:15]1[C:24]2[C:19](=[CH:20][C:21]([O:27][CH3:28])=[C:22]([O:25][CH3:26])[CH:23]=2)[N:18]=[C:17]([N:29]2[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]2)[N:16]=1>>[ClH:13].[NH2:14][C:15]1[C:24]2[C:19](=[CH:20][C:21]([O:27][CH3:28])=[C:22]([O:25][CH3:26])[CH:23]=2)[N:18]=[C:17]([N:29]2[CH2:34][CH2:33][N:32]([C:11]([C:9]3[O:10][C:6]([S:5][CH2:1][CH2:2][CH2:3][CH3:4])=[N:7][N:8]=3)=[O:12])[CH2:31][CH2:30]2)[N:16]=1참가 물질
3
실험 절차
The title compound was prepared from 5-n-butylthio-1,3,4-oxadiazole-2-carbonyl chloride and 4-amino-6,7-dimethoxy-2-(1-piperazinyl)quinazoline following the procedure of Example 1.
출처 및 근거
- ORD 기록
- ord-88321969b57845a3b3f99a248829297a
- 출처 데이터셋
- uspto-grants-1977_01