Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Toluenesulfonyl chloride → N,N-bis(2-(p-toluenesulfonyloxy)ethyl)-p-toluenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| 반응물 | N,N-Bis(2-hydroxyethyl)-4-methylbenzenesulfonamide | HCID 81565 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | N,N-bis(2-(p-toluenesulfonyloxy)ethyl)-p-toluenesulfonamide | HCID 267409 | — |
반응 단계
Procedure 3 is illustrated with the preparation of (-)-(RR)-8a' and (+)-(RR)-8b', with (-)-(R)-6f' as a byproduct. In dry pyridine at 0°, N,N-bis-(2-hydroxyethyl)-p-toluenesulfonamide (m.p. 96°-99°) was tosylated with tosyl chloride by the standard method to give N,O,O'-tritosyldiethanolamine, m.p. 85°-87°. [Can. J. Chem. 45, 1555 (1967) gives 78°-79°].
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04001279 |
| 출처 데이터셋 | uspto-grants-1977_01 |
| ORD ID | ord-0ab10b2563654590921d806eedcd1473 |
| 출처 메모 | uspto-grants-1977_01 |