Water → 4,8-Dimethyl-deca-1,6-dien-3-ol

HRID 1414461노트

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HRID 1414461 반응식
[CH3:1][CH:2]([CH2:5][CH:6]=[CH:7][CH:8]([CH3:11])[CH2:9][CH3:10])[CH:3]=[O:4].[CH:12]([Mg]Cl)=[CH2:13].O>O1CCCC1>[CH3:1][CH:2]([CH2:5][CH:6]=[CH:7][CH:8]([CH3:11])[CH2:9][CH3:10])[CH:3]([OH:4])[CH:12]=[CH2:13]

참가 물질

5

반응물 3

HCID 962WaterHCID 538397432,6-Dimethyl-oct-4-en-1-alHCID 178461836HCID 178461836, 화합물

생성물 1

HCID 542471304,8-Dimethyl-deca-1,6-dien-3-ol수율 94%

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

54 g (0.35 mole) of 2,6-dimethyl-oct-4-en-1-al are added in the course of 15 minutes to a solution of 0.4 mole of vinyl-magnesium chloride in 2 liters of tetrahydrofuran, whilst cooling with ice. After a reaction time of 30 minutes, the mixture is hydrolyzed with 40 ml of water, the organic phase is isolated and the solvent is distilled off. The reaction product is fractionated, giving 60 g of the above allyl alcohol (yield, 94% of theory). B.p. = 48°-52° C at 0.02 mm Hg; nD25 = 1.4591.

후처리

  1. temperaturewhilst cooling with ice
  2. customAfter a reaction time of 30 minutes
  3. customthe organic phase is isolated
  4. distillationthe solvent is distilled off

출처 및 근거

ORD 기록
ord-dc95a4cd33f74c54bc31df8af529958e
출처 데이터셋
uspto-grants-1977_01
특허 번호
US04001336

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