Potassium Carbonate → HCID 21487992, 화합물

HRID 1414611노트

반응식

HRID 1414611 반응식
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]3[CH:26]=[CH:25][CH:24]=[CH:23][C:11]=3[C:12]=2[C:13](=[O:22])[C:14]2[CH:19]=[C:18]([CH3:20])[CH:17]=[C:16]([CH3:21])[CH:15]=2)=[CH:4][CH:3]=1.C(=O)([O-])[O-].[K+].[K+].[CH2:33]([N:35]([CH2:39][CH3:40])[CH2:36][CH2:37]Cl)[CH3:34]>CC(C)=O>[CH2:33]([N:35]([CH2:39][CH3:40])[CH2:36][CH2:37][O:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:9][C:10]3[CH:26]=[CH:25][CH:24]=[CH:23][C:11]=3[C:12]=2[C:13](=[O:22])[C:14]2[CH:15]=[C:16]([CH3:21])[CH:17]=[C:18]([CH3:20])[CH:19]=2)=[CH:6][CH:7]=1)[CH3:34]

참가 물질

5

반응물 3

HCID 11430Potassium CarbonateHCID 13364Diethylaminoethyl chlorideHCID 21487920HCID 21487920, 화합물

생성물 1

HCID 21487992HCID 21487992, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

2-p-Hydroxyphenyl-3-(3',5'-dimethylbenzoyl)benzofuran (5.25 g., 15.3 mmol.) was dissolved in 200 ml. of dry acetone and 10.5 g. (0.076 mol.) of potassium carbonate and 2.10 g. (15.3 mmol.) of 2-diethylaminoethyl chloride were added. The reaction mixture was refluxed for three hours, then it was cooled and filtered. The filtrate was concentrated at reduced pressure to give the title compound as an oil.

후처리

  1. temperatureThe reaction mixture was refluxed for three hours
  2. temperatureit was cooled
  3. filtrationfiltered
  4. concentrationThe filtrate was concentrated at reduced pressure

출처 및 근거

ORD 기록
ord-f3021689b5424ac09203357e407fc367
출처 데이터셋
uspto-grants-1977_01
특허 번호
US04001426

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