Diethyl Ether → HCID 54574644, 화합물

HRID 1414837노트

반응식

[CH2:1]([Mg]Br)[CH:2]=[CH2:3].[CH:6]12[CH2:12][CH:9]([CH:10]=[CH:11]1)[CH:8]=[CH:7]2.C([O:15]CC)C>>[CH:2]12[CH2:1][CH:9]([CH:10]=[CH:11]1)[CH:8]1[CH:3]2[CH:6]([CH2:12][OH:15])[CH2:7]1

참가 물질

반응물 3

HCID 3283Diethyl Ether

HCID 8473Norbornadiene

HCID 178455850HCID 178455850, 화합물

생성물 1

HCID 54574644HCID 54574644, 화합물수율 73%

실험 절차

The procedure of Example I was repeated on a larger scale by reacting 195 mmoles of allylmagnesium bromide in diethyl ether with 218 mmoles of bicyclo[2.2.1]hepta-2,5-diene at 125° C. for 3 hours. After the oxidation and hydrolysis, distillation gave tricyclo[4.2.1.02.5 ]non-7-en-3-yl-methanol (b.p. 97°-99° C. at 1 mm Hg) in 73 percent yield based on the allylmagnesium bromide.

후처리

customat 125° C.
customfor 3 hours
customAfter the oxidation and hydrolysis, distillation

출처 및 근거

ORD 기록: ord-ee87587f7e3e405e8575e72d6ae99334
출처 데이터셋: uspto-grants-1977_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04002691

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