Bromine → 2-[Bromo(nitro)methylidene]-1-methylimidazolidine

HRID 1414899노트

반응식

HRID 1414899 반응식
[CH3:1][N:2]1[CH2:6][CH2:5][NH:4][C:3]1=[CH:7][N+:8]([O-:10])=[O:9].[Br:11]Br>O>[Br:11][C:7]([N+:8]([O-:10])=[O:9])=[C:3]1[NH:4][CH2:5][CH2:6][N:2]1[CH3:1]

참가 물질

4

반응물 2

HCID 24408BromineHCID 702500461-Methyl-2-(nitromethylidene)imidazolidine2회

생성물 1

HCID 706389552-[Bromo(nitro)methylidene]-1-methylimidazolidine

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A stirred solution of 3.57 grams of 1-methyl-2-(nitromethylene)imidazolidine (Compound 1) in 25 milliliters of water was treated dropwise with 3.99 grams of bromine at room temperature. After 30 minutes, the reaction mixture was extracted with methylene chloride. The extract was dried (MgSO4) and the solvent was evaporated to give 3.0 grams of crude product, melting point 100° (with vigorous decomposition). Recrystallization of the crude product from methylene chloride gave 15, melting point: 97° (explodes).

후처리

  1. extractionthe reaction mixture was extracted with methylene chloride
  2. dry with materialThe extract was dried (MgSO4)
  3. customthe solvent was evaporated
  4. customto give 3.0 grams of crude product, melting point 100° (with vigorous decomposition)
  5. customRecrystallization of the crude product from methylene chloride

출처 및 근거

ORD 기록
ord-7e03460326854d94987b1724353d4b8f
출처 데이터셋
uspto-grants-1977_01
특허 번호
US04002765

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