Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 1,2-Diamino-4-(pyrimidin-2-ylthio)benzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Potassium Bicarbonate | HCID 516893 | — |
| 반응물 | 2-Nitro-5-[(pyrimidin-2-yl)sulfanyl]aniline | HCID 21482775 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 1,2-Diamino-4-(pyrimidin-2-ylthio)benzene | HCID 21482779 | — |
반응 단계
3.5 G. of 2-amino-1-nitro-4-(pyrimidin-2-ylthio)benzene is treated with 16 g. stannous chloride in 16 ml. concentrated hydrochloric acid on the steam bath for 30 minutes. The mixture is cooled, treated with an excess of potassium bicarbonate, chloroform, and filtered. The chloroform layer is dried and stripped yielding 1,2-diamino-4-(pyrimidin-2-ylthio)benzene which may be recrystallized from benzene.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04005202 |
| 출처 데이터셋 | uspto-grants-1977_01 |
| ORD ID | ord-9e608459653b47e88ce7dbe770e09bbd |
| 출처 메모 | uspto-grants-1977_01 |