Ethanol → 3-Methyl-4-(prop-2-en-1-yl)-1-(alpha-methyl-3,4-di-chlorobenzyl)-pyrazol-5-one

HRID 1415593

반응식

HRID 1415593 반응식
C(OC(=O)C[C:6]([CH2:8][CH2:9][CH:10]=[CH2:11])=[O:7])C.[CH3:13][CH:14]([NH:23][NH2:24])[C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[C:17]([Cl:22])[CH:16]=1.[CH2:25](O)[CH3:26]>>[CH3:25][C:26]1[NH:24][N:23]([CH:14]([CH3:13])[C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[C:17]([Cl:22])[CH:16]=2)[C:6](=[O:7])[C:8]=1[CH2:9][CH:10]=[CH2:11]

참가 물질

4

반응물 3

HCID 702EthanolHCID 247666Ethyl 3-oxo-6-heptenoateHCID 3016950(1-(3,4-Dichlorophenyl)ethyl)hydrazine

생성물 1

HCID 203619413-Methyl-4-(prop-2-en-1-yl)-1-(alpha-methyl-3,4-di-chlorobenzyl)-pyrazol-5-one

실험 절차

17 g (0.1 mol) of allylacetoacetic acid ethyl ester were added to a mixture of 20.5 g of α-methyl-3,4-dichlorobenzylhydrazine and 30 ml of absolute ethanol under nitrogen, whereupon the temperature rose to 55° C. The reaction mixture was heated to the reflux temperature for 2 hours. After cooling, the reaction product crystallized out.

후처리

  1. customrose to 55° C
  2. temperatureThe reaction mixture was heated to the reflux temperature for 2 hours
  3. temperatureAfter cooling
  4. customthe reaction product crystallized out

출처 및 근거

ORD 기록
ord-6ee7a292affc42ad96f35175ca3f9164
출처 데이터셋
uspto-grants-1977_01
특허 번호
US04005215

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