1-(4-Methoxyphenyl)-4-Methyl-2-(4-sulfamoylphenyl)pyrrole → 3-Benzoylpropionitrile

HRID 1415735

반응식

HRID 1415735 반응식
Cl[C:2]1[CH:3]=[C:4]([C:10]2[N:11](C3C=C[C:19]([S:22](=O)(=O)N)=CC=3)[CH:12]=[C:13](C)[CH:14]=2)[CH:5]=[CH:6][C:7]=1OC.C[O:27][C:28]1[CH:33]=[CH:32][C:31]([N:34]2[CH:38]=[C:37]([CH3:39])[CH:36]=[C:35]2[C:40]2[CH:45]=[CH:44][C:43]([S:46](=[O:49])(=[O:48])[NH2:47])=[CH:42][CH:41]=2)=[CH:30][CH:29]=1>>[CH2:14]([CH2:13][C:12]#[N:11])[C:10]([C:4]1[CH:5]=[CH:6][CH:7]=[CH:2][CH:3]=1)=[O:27].[CH3:39][C:37]1[CH:36]=[C:35]([C:40]2[CH:45]=[CH:44][C:43]([S:46](=[O:49])(=[O:48])[NH2:47])=[CH:42][CH:41]=2)[N:34]([C:31]2[CH:32]=[CH:33][C:28]([S:22][CH3:19])=[CH:29][CH:30]=2)[CH:38]=1

참가 물질

4

반응물 2

HCID 218627931-(4-Methoxyphenyl)-4-Methyl-2-(4-sulfamoylphenyl)pyrroleHCID 218628462-(3-Chloro-4-methoxyphenyl)-4-methyl-1-(4-sulfamoylphenyl)pyrrole

생성물 2

HCID 1384653-BenzoylpropionitrileHCID 99287494-Methyl-1-(4-methylthiophenyl)-2-(4-sulfamoylphenyl)pyrrole

실험 절차

In this Step, a phenacyl acetonitrile compound of formula (17) is prepared by alkylating the cyano compound of formula (16) with a phenacyl halide compound of formula (7). This reaction is essentially the same as and may be carried out in the same manner as and using the same reagents and reaction conditions as Step B3 of Method B.

후처리

  1. customthe same reagents and reaction conditions as Step B3 of Method B

출처 및 근거

ORD 기록
ord-a257620a77224c62b266e2081366570a
출처 데이터셋
uspto-grants-1999_06
특허 번호
US05908858

연결된 노트

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