[1-Benzyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazol-2-yl]methanol → 2-Aminomethyl-1-benzyl-5-(3,5-dichlorophenylthio)-4-isopropylimidazole
반응식
[CH2:1]([N:8]1[C:12]([S:13][C:14]2[CH:19]=[C:18]([Cl:20])[CH:17]=[C:16]([Cl:21])[CH:15]=2)=[C:11]([CH:22]([CH3:24])[CH3:23])[N:10]=[C:9]1[CH2:25]Cl)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C([N:34]1C(SC2C=C(Cl)C=C(Cl)C=2)=C(C(C)C)N=C1CO)C1C=CC=CC=1>>[NH2:34][CH2:25][C:9]1[N:8]([CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[C:12]([S:13][C:14]2[CH:15]=[C:16]([Cl:21])[CH:17]=[C:18]([Cl:20])[CH:19]=2)=[C:11]([CH:22]([CH3:23])[CH3:24])[N:10]=1참가 물질
3
실험 절차
1-Benzyl-2-chloromethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazole (28e)was synthesized from [1-benzyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazol-2-yl]methanol by the same synthetic process as that for (28a)in Example 66, and without purification of this compound, 2-azidomethyl-1-benzyl-5-(3,5-dichlorophenylthio)-4-isopropylimidazole (29e)was obtained by the same synthetic process as that for (29a)in Example 66. Oil.