Sodium Methoxide → 3-((1-methyl-2-(S)-pyrrolidinyl)methoxy)-5methoxy-pyridine-N-oxide
반응식
[CH3:1][N:2]1[CH2:6][CH2:5][CH2:4][C@H:3]1[CH2:7][O:8][C:9]1[CH:10]=[N+:11]([O-:16])[CH:12]=[C:13](Br)[CH:14]=1.[CH3:17][O-:18].[Na+]>CO>[CH3:1][N:2]1[CH2:6][CH2:5][CH2:4][C@H:3]1[CH2:7][O:8][C:9]1[CH:10]=[N+:11]([O-:16])[CH:12]=[C:13]([O:18][CH3:17])[CH:14]=1참가 물질
4
실험 절차
A sample of the compound from step 98a above is reacted with sodium methoxide in methanol according to standard procedures. The reaction is quenched with water, the product is extracted, then purified by chromatography on silica gel.
후처리
- customThe reaction is quenched with water
- extractionthe product is extracted
- custompurified by chromatography on silica gel
출처 및 근거
- ORD 기록
- ord-1d450716c2c64c538c2ac86dc76cce6f
- 출처 데이터셋
- uspto-grants-1999_06
- 특허 번호
- US05914328
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