2-Acetamino-3-oxooctadecanoic acid → N-(1,3-dihydroxyoctadecan-2-yl)acetamide

반응식

[NH:1]([CH:5]([C:9](=[O:25])[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[C:6](O)=[O:7])[C:2]([CH3:4])=[O:3].[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[NH:1]([CH:5]([CH:9]([OH:25])[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[CH2:6][OH:7])[C:2]([CH3:4])=[O:3]

참가 물질

반응물 2

HCID 186251832-Acetamino-3-oxooctadecanoic acid

HCID 21226445Aluminium lithium hydride

생성물 1

HCID 2506N-(1,3-dihydroxyoctadecan-2-yl)acetamide

실험 절차

As shown below, the ester and ketone groups in an ester of 2-acetamino-3-oxooctadecanoic acid are reduced in the presence of lithium aluminium hydride (referred to as LAH) to obtain a racemate of 2-acetaminooctadecane-1,3-diol, as follows: ##STR7##

출처 및 근거

ORD 기록: ord-fc484f13a60d49f0b2093d8639ec0a45
출처 데이터셋: uspto-grants-1999_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05916578

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