2-[4-(4-Nitrophenoxy)butyl]-1H-isoindole-1,3(2H)-dione → HCID 3030019, 화합물

HRID 1417313노트

반응식

HRID 1417313 반응식
[N+:1]([C:4]1[CH:25]=[CH:24][C:7]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][N:13]2[C:21](=[O:22])[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[C:14]2=[O:23])=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][N:13]2[C:14](=[O:23])[C:15]3[C:20](=[CH:19][CH:18]=[CH:17][CH:16]=3)[C:21]2=[O:22])=[CH:24][CH:25]=1

참가 물질

4

반응물 1

HCID 161051422-[4-(4-Nitrophenoxy)butyl]-1H-isoindole-1,3(2H)-dione

생성물 1

HCID 3030019HCID 3030019, 화합물

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

A suspension of 6.8 g of 2-[4-(4-nitro-phenoxy)butyl]-1H-isoindole-1,3(2H)-dione (Example 33) in 200 ml of ethanol is treated with 500 mg of 10% Pd on carbon, and reduced in a Parr hydrogenator. After filtration, concentration of the filtrate gives the desired product, m.p. 119°-121° C.; yield 4.3 g.

후처리

  1. filtrationAfter filtration, concentration of the filtrate

출처 및 근거

ORD 기록
ord-6de960758f5445b888ed99468905e9ac
출처 데이터셋
uspto-grants-1999_03
특허 번호
US05877196

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