Isobutyramide → N-[2-t-Butyl-5-(2-methylpropanoyl)aminocarbonylphenyl)-3-(2,4-dimethoxyphenyl)octanamide
반응식
[C:1]([C:5]1[CH:10]=CC(C(O)=O)=C[C:6]=1[NH:14][C:15](=[O:33])[CH2:16][CH:17]([C:23]1[CH:28]=[CH:27][C:26]([O:29][CH3:30])=[CH:25][C:24]=1[O:31][CH3:32])[CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])([CH3:4])([CH3:3])[CH3:2].[CH3:34][CH:35]([CH3:39])[C:36]([NH2:38])=[O:37]>C(#N)C>[C:1]([C:5]1[CH:10]=[CH:39][C:35]([C:36]([NH:38][C:24](=[O:31])[CH:23]([CH3:28])[CH3:17])=[O:37])=[CH:34][C:6]=1[NH:14][C:15](=[O:33])[CH2:16][CH:17]([C:23]1[CH:28]=[CH:27][C:26]([O:29][CH3:30])=[CH:25][C:24]=1[O:31][CH3:32])[CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])([CH3:4])([CH3:2])[CH3:3]참가 물질
4
실험 절차
Following a similar procedure to that described in Example 139, but using N-(2-t-butyl-5-carboxyphenyl)-3-(2,4-dimethoxyphenyl)octanamide (prepared as described in Preparation 7) and 2-methylpropanamide, the title compound was obtained as crystals, melting at 157°-159° C. (from acetonitrile).