Ethylene Glycol → HCID 57081597, 화합물

HRID 1418364

반응식

HRID 1418364 반응식
[CH:1]([C:3]1[CH:10]=[CH:9][CH:8]=[CH:7][C:4]=1[CH:5]=[O:6])=[CH2:2].C[Si](Cl)(C)C.[CH2:16](O)[CH2:17][OH:18]>C(=O)(O)[O-].[Na+]>[CH2:17]1[O:18][CH:5]([C:4]2[CH:7]=[CH:8][CH:9]=[CH:10][C:3]=2[CH:1]=[CH2:2])[O:6][CH2:16]1

참가 물질

5

반응물 3

HCID 174Ethylene GlycolHCID 6397ChlorotrimethylsilaneHCID 39391Benzaldehyde, 2-ethenyl-

생성물 1

HCID 57081597HCID 57081597, 화합물

시약·촉매·용매 1

HCID 516892Sodium Bicarbonate용매

실험 절차

A mixture of 2-vinylbenzaldehyde (2.9 g, 22 mmol) and trimethylsilyl chloride (11 ml) in ethylene glycol (95 ml) was stirred for 16 h, diluted with saturated sodium bicarbonate solution, extracted with ether, dried over sodium sulphate and evaporated to afford a colourless oil (2.7 g), MS (+EI) 176 (M+), 1H NMR (CDCl3) 7.57 (1H, m), 7.53 (1H, dd, J1.5, 7.5 Hz), 7.36-7.30 (2H, m), 7.14 (1H, dd, J11, 17.4 Hz), 6.04 (1H, s) 5.69 (1H, dd, J1.3, 17.4 Hz), 5.34 (1H, dd, J1.3, 11.0 Hz), 4.18-4.04 (2H, m), 3.77-3.65 (2H, m).

후처리

  1. extractionextracted with ether
  2. dry with materialdried over sodium sulphate
  3. customevaporated

출처 및 근거

ORD 기록
ord-af51443a925a48a791f16128fb1ca950
출처 데이터셋
uspto-grants-1999_03
특허 번호
US05883102

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