HCID 22008823, 화합물 → HCID 67568419, 화합물

반응식

C1O[C:4]2([CH2:9][CH2:8][N:7]([C:10](=[O:19])[C:11]3[CH:16]=[CH:15][C:14]([C:17]#[N:18])=[CH:13][CH:12]=3)[CH2:6][CH2:5]2)OC1.[ClH:21].Cl.[NH2:23][C:24]1[CH:32]=[CH:31][CH:30]=[C:29]([F:33])[C:25]=1[C:26]([NH2:28])=[NH:27]>>[ClH:21].[C:17]([C:14]1[CH:13]=[CH:12][C:11]([C:10]([N:7]2[CH2:6][CH2:5][C:4]3([N:27]=[C:26]([NH2:28])[C:25]4[C:24](=[CH:32][CH:31]=[CH:30][C:29]=4[F:33])[NH:23]3)[CH2:9][CH2:8]2)=[O:19])=[CH:16][CH:15]=1)#[N:18]

참가 물질

반응물 2

HCID 22008823HCID 22008823, 화합물

HCID 35370604HCID 35370604, 화합물

생성물 1

HCID 67568419HCID 67568419, 화합물

실험 절차

This was prepared from 1-(4-cyanobenzoyl)-4-piperidone ethylene ketal (Example U(b)) and 2-amino-6-fluorobenzamidine dihydrochloride (Example C) by the method of Example 1, to give the title compound as pale yellow crystals, m.p. 299°-300° C.

출처 및 근거

ORD 기록: ord-cefa7b1dd1904c9db0945c2e03ab3e99
출처 데이터셋: uspto-grants-1999_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05883102

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