Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-Dichloroacetone → 4-(Chloromethyl)-2-(3,4-dimethoxyphenyl)-1,3-thiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-Dichloroacetone | HCID 10793 | — |
| 반응물 | 3,4-Dimethoxythiobenzamide | HCID 2758490 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4-(Chloromethyl)-2-(3,4-dimethoxyphenyl)-1,3-thiazole | HCID 2079396 | 59.1% |
반응 단계
1.5 g of 1,3-dichloroacetone and 2.3 g of 3,4-dimethoxythiobenzamide were suspended in 100 ml of ethanol. The suspension was heated for 3 hours to complete the reaction. The solvent was removed by distillation. The residue was purified by silica gel column chromatography to obtain 1.86 g of 2-(3,4-dimethoxyphenyl)-4-chloromethylthiazole as a colorless viscous oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06080764 |
| 출처 데이터셋 | uspto-grants-2000_06 |
| ORD ID | ord-5498671472d94442b51712a9af07884e |
| 출처 메모 | uspto-grants-2000_06 |