Water → HCID 18706342, 화합물

HRID 1422218노트

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HRID 1422218 반응식
[N-:1]=[N+:2]=[N-:3].[Na+].[Br:5][C:6]1[CH:15]=[C:14]2[C:9]([N:10]=[C:11]([O:18][CH3:19])[C:12]([O:16][CH3:17])=[N:13]2)=[C:8]([CH2:20]Br)[CH:7]=1.O>CN(C)C=O>[N:1]([CH2:20][C:8]1[CH:7]=[C:6]([Br:5])[CH:15]=[C:14]2[C:9]=1[NH:10][CH:11]([O:18][CH3:19])[CH:12]([O:16][CH3:17])[NH:13]2)=[N+:2]=[N-:3]

참가 물질

5

반응물 3

HCID 962WaterHCID 33557Sodium AzideHCID 23298010HCID 23298010, 화합물

생성물 1

HCID 18706342HCID 18706342, 화합물

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

743 mg (2 equiv.) of sodium azide are added at 20° C. to 2.07 g (5.72 mmol) of 7-bromo-5-bromomethyl-2,3-dimethoxy-quinoxaline in 25 ml of dimethylformamide. After 3 hours, the mixture is poured into water, extracted with diethyl ether, washed with water and brine and dried with magnesium sulfate. The solvent is concentrated by evaporation.

후처리

  1. extractionextracted with diethyl ether
  2. washwashed with water and brine
  3. dry with materialdried with magnesium sulfate
  4. concentrationThe solvent is concentrated by evaporation

출처 및 근거

ORD 기록
ord-4c0138fec2b24723b437e1bc47e03591
출처 데이터셋
uspto-grants-2000_06
특허 번호
US06080743

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