4-Bromo-3,5-dimethyl-1,2-oxazole → 2-Chloro-4-(3,5-dimethyl-isoxazol-4-yl)-pyridine

HRID 1422413노트

반응식

HRID 1422413 반응식
Br[C:2]1[C:3]([CH3:8])=[N:4][O:5][C:6]=1[CH3:7].[Cl:9][C:10]1[CH:15]=[C:14](C2C=NN(C3CCCCO3)C=2)[CH:13]=[CH:12][N:11]=1>>[Cl:9][C:10]1[CH:15]=[C:14]([C:2]2[C:3]([CH3:8])=[N:4][O:5][C:6]=2[CH3:7])[CH:13]=[CH:12][N:11]=1

참가 물질

3

반응물 2

HCID 3184214-Bromo-3,5-dimethyl-1,2-oxazoleHCID 595343552-Chloro-4-[1-(tetrahydro-pyran-2-yl)-1H-pyrazol-4-yl]-pyridine

생성물 1

HCID 595344492-Chloro-4-(3,5-dimethyl-isoxazol-4-yl)-pyridine

실험 절차

The title compound was prepared from 4-bromo-3,5-dimethylisoxazole generally according to the synthetic procedure described for 2-Chloro-4-[1-(tetrahydro-pyran-2-yl)-1H-pyrazol-4-yl]-pyridine. HPLC (Rt)=0.81 min (method N)

후처리

  1. customHPLC (Rt)=0.81 min (method N)

출처 및 근거

ORD 기록
ord-c0508a5dcc9945de9147310e74c962ad
출처 데이터셋
uspto-grants-2015_01
특허 번호
USRE045323E1

반응 노트

불러오는 중…