6-((S)-3-benzyl-piperazin-1-yl)-1-isopropyl-3-ethyl-1H-indazole → HCID 178437955, 화합물
반응식
[N:1]1[N:2]=[C:3]([CH2:6][C:7]([O:9]CC)=O)[NH:4][CH:5]=1.[CH2:12]([C@@H:19]1[NH:24][CH2:23][CH2:22][N:21]([C:25]2[CH:33]=[C:32]3[C:28]([C:29]([CH2:37][CH3:38])=[N:30][N:31]3[CH:34]([CH3:36])[CH3:35])=[CH:27][CH:26]=2)[CH2:20]1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[CH2:12]([C@H:19]1[CH2:20][N:21]([C:25]2[CH:33]=[C:32]3[C:28]([C:29]([CH2:37][CH3:38])=[N:30][N:31]3[CH:34]([CH3:35])[CH3:36])=[CH:27][CH:26]=2)[CH2:22][CH2:23][N:24]1[C:7](=[O:9])[CH2:6][C:3]1[NH:4][CH:5]=[N:1][N:2]=1)[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1참가 물질
3
실험 절차
Prepared by the method outlined for Example 275 using ethyl 2-(4H-1,2,4-triazol-3-yl)acetate and 6-((S)-3-benzyl-piperazin-1-yl)-1-isopropyl-3-ethyl-1H-indazole as starting materials. Product was obtained as an off-white solid (39%). LC/MS (Method B) 3.34 min, [M+1]+ 472.
후처리
- customPrepared by the method
출처 및 근거
- ORD 기록
- ord-9af2b489cba04d0d83aa3699983ffaf6