2-(3-methyl-1H-1,2,4-triazol-5-yl)acetic acid → HCID 178491986, 화합물
반응식
[CH2:1]([C@@H:8]1[NH:13][CH2:12][CH2:11][N:10]([C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[C:16]([O:22][CH:23]3[CH2:25][CH2:24]3)[CH:15]=2)[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:26][C:27]1[NH:31][N:30]=[C:29]([CH2:32][C:33](O)=[O:34])[N:28]=1>>[CH2:1]([C@H:8]1[CH2:9][N:10]([C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[C:16]([O:22][CH:23]3[CH2:25][CH2:24]3)[CH:15]=2)[CH2:11][CH2:12][N:13]1[C:33](=[O:34])[CH2:32][C:29]1[NH:30][N:31]=[C:27]([CH3:26])[N:28]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1참가 물질
3
실험 절차
Prepared using the same procedure described in Example 189 from (S)-3-benzyl-1-(3-cyclopropoxy-4-methoxy-phenyl)-piperazine and (5-methyl-1H-[1,2,4]triazol-3-yl)-acetic acid to afford the title compound as colorless solid (53 mg, 40%). LC/MS (Method B) 3.02 min, [M+1]+ 462.
후처리
- customPrepared
출처 및 근거
- ORD 기록
- ord-66eccf09d5b1478a8bbd6eb3e162261b