Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
7-Bromo-1-Chloroisoquinoline → 7-bromo-2-(N-propylamino)isoquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 7-Bromo-1-Chloroisoquinoline | HCID 6502024 | — |
| 용매 | Propylamine | HCID 7852 | — |
| 생성물 | 7-bromo-2-(N-propylamino)isoquinoline | HCID 21085996 | — |
반응 단계
A solution of 7-bromo-1-chloroisoquinoline in propylamine (15.0 mL) was heated at 70° C. in a sealed tube overnight. The reaction mixture was concentrated under reduced pressure, then dissolved in chloroform and washed with saturated sodium bicarbonate, saturated sodium chloride, dried (sodium sulfate), filtered, and concentrated under reduced pressure to yield 7-bromo-2-(N-propylamino)isoquinoline (820 mg): ESI MS m/z 266 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07727997B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-d4e7541abda242baa613fc8098349853 |
| 출처 메모 | uspto-grants-2010_06 |